Advanced Vector Extensions
Advanced Vector Extensions (AVX) are instruction set extensions introduced by Intel in 2011.
Expanding most integer commands to 256 bits.
They add 512-bit vector operations capabilities in 2013, with up to 2 FMAs (Fused Multiply Add instructions), to accelerate performance of demanding computational tasks.
AVX-512 instructions are used by optimized primality testing software like Prime95 and Mlucas to increase performance.
Machines with AVX-512 capabilities were used to verify M50 at the time of its discovery. 
As of April 2018, some of the processors supporting AVX-512:
- Intel Xeon Phi x200 (Knights Landing)
- Intel's Skylake-X CPUs
- some CPUs from the Intel Core-X series (such as i7-7800X)
- Intel Xeon D-2100